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· 0 checks — Desktop Lighthouse audit -- Performance, Accessibility, Best Practices, and SEO category breakdown.
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Detailed Report

Audit breakdown by category with detailed findings.

70

Performance

Insights

Remove large, duplicate JavaScript modules from bundles to reduce unnecessary bytes consumed by network activity.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Polyfills and transforms enable older browsers to use new JavaScript features. However, many aren't necessary for modern browsers. Consider modifying your JavaScript build process to not transpile Baseline features, unless you know you must support older browsers. Learn why most sites can deploy ES6+ code without transpiling

Why this matters

Performance issues directly impact user engagement and conversion rates.

3rd party code can significantly impact load performance. Reduce and defer loading of 3rd party code to prioritize your page's content.

Why this matters

Performance issues directly impact user engagement and conversion rates.

A long cache lifetime can speed up repeat visits to your page. Learn more about caching.

Why this matters

Performance issues directly impact user engagement and conversion rates.

RequestCache TTLTransfer Size
/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759...0.0 ms347.9 KiB
/assets/fontawesome-webfont-fa79d127baca4558a0b973f5f514b...0.0 ms75.6 KiB
/assets/ie8/application-8c033a599105d459c98ea08bf9ef15e25...0.0 ms62.1 KiB
/assets/application-4e3473ed7442aa1dc35d11f58ed4edfbd690f...0.0 ms47.2 KiB
dm5migu4zj3pb.cloudfront.net/fonts/klavika/woff/KlavikaWebBasicRegular.woff0.0 ms42.2 KiB
dm5migu4zj3pb.cloudfront.net/fonts/klavika/woff/KlavikaWebBasicBold.woff0.0 ms38.8 KiB
dm5migu4zj3pb.cloudfront.net/volumes/136/8/136-8-cover.jpg0.0 ms33.7 KiB
/vi/71EQZ3rSZ8g/sddefault.jpg?sqp=-oaymwEmCIAFEOAD8quKqQM...7200.0 s31.9 KiB
/assets/ie8/application-c9c1df9dc6f969fb6db3e6e1316b9ac16...0.0 ms21.4 KiB
/assets/common/jci-spelled-out-white-on-transparent.20160...0.0 ms16.2 KiB
www.google-analytics.com/analytics.js7200.0 s20.9 KiB
/assets/ie8/ie8-head-e4cc6664a4e806f330a789c9756cfe50f1bb...0.0 ms13.9 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198730/small/JCI198730.ga.gif0.0 ms10.3 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/201000/201075/small/JCI201075.f1.gif0.0 ms10.1 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198835/small/JCI198835.f1.gif0.0 ms8.2 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194139/small/JCI194139.ga.gif0.0 ms7.7 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/202000/202577/small/JCI202577.f1.gif0.0 ms7.1 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/195000/195411/small/JCI195411.f1.gif0.0 ms7.0 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198076/small/JCI198076.ga.gif0.0 ms6.9 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199850/small/JCI199850.f1.gif0.0 ms6.8 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/206000/206748/small/JCI206748.f1.gif0.0 ms6.7 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198815/small/JCI198815.ga.gif0.0 ms6.4 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194721/small/JCI194721.ga.gif0.0 ms6.2 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199035/small/JCI199035.ga.gif0.0 ms6.0 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/191000/191735/small/JCI191735.ga.gif0.0 ms6.0 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198708/small/JCI198708.ga.gif0.0 ms5.8 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197271/small/JCI197271.ga.gif0.0 ms5.4 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/196000/196788/small/JCI196788.ga.gif0.0 ms4.9 KiB
/assets/vendor/modernizr-2f68aa04c7424c280c5bc9db8b68f7f6...0.0 ms4.7 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/205000/205273/small/JCI205273.f1.gif0.0 ms4.6 KiB
/assets/search-black-ba9b554d6f74b1c93d6e6ab71d1c9830c18a...0.0 ms4.5 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/205000/205029/small/JCI205029.f1.gif0.0 ms4.5 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197923/small/JCI197923.ga.gif0.0 ms4.5 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/196000/196819/small/JCI196819.ga.gif0.0 ms4.5 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197556/small/JCI197556.ga.gif0.0 ms4.3 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/189000/189044/small/JCI189044.ga.gif0.0 ms4.3 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197812/small/JCI197812.ga.gif0.0 ms4.2 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199725/small/JCI199725.f1.gif0.0 ms4.1 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/200000/200062/small/JCI200062.ga.gif0.0 ms4.0 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194207/small/JCI194207.ga.gif0.0 ms3.9 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/205000/205442/small/JCI205442.f1.gif0.0 ms3.9 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/193000/193812/small/JCI193812.ga.gif0.0 ms3.7 KiB
/assets/social/twitter-round-blue-78025a92064e3594e44e4cc...0.0 ms3.4 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197503/small/JCI197503.ga.gif0.0 ms3.4 KiB
dm5migu4zj3pb.cloudfront.net/manuscripts/201000/201762/small/JCI201762.ga.gif0.0 ms3.3 KiB
/assets/social/facebook-round-blue-2787910d46dcbdbee4bd34...0.0 ms3.1 KiB
/assets/social/rss-round-color-6f5fa8e93dc066ee4923a36ba6...0.0 ms2.8 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/29.png0.0 ms2.3 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/38.png0.0 ms2.3 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/46.png0.0 ms2.3 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/50.png0.0 ms2.3 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/66.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/8.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/6.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/2.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/3.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/5.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/4.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/7.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/11.png0.0 ms2.2 KiB
d1uo4w7k31k5mn.cloudfront.net/v2_hq/1.png0.0 ms2.1 KiB
/assets/common/search-white-530f3f95b9080d73eba51eaeffdf1...0.0 ms1.9 KiB
/assets/ie8/ie8-1af1fadfa0df4a7f5fcf8fc444742398e0579e1d8...0.0 ms1.5 KiB
d1bxh8uas1mnw7.cloudfront.net/assets/embed.js0.0 ms1.0 KiB
/v1/internal-556fdf0f/doi/10.1172/jci205273?callback=_alt...3600.0 s710 B
/v1/internal-556fdf0f/doi/10.1172/jci194207?callback=_alt...3600.0 s694 B
/v1/internal-556fdf0f/doi/10.1172/jci197503?callback=_alt...3600.0 s683 B
/assets/common/jci-only-white-6c989e8f9744a714482158b8231...0.0 ms522 B
static.doubleclick.net/instream/ad_status.js900.0 s494 B
/v1/internal-556fdf0f/doi/10.1172/jci206633?callback=_alt...3600.0 s481 B
/v1/internal-556fdf0f/doi/10.1172/jci197556?callback=_alt...3600.0 s475 B
/v1/internal-556fdf0f/doi/10.1172/jci197812?callback=_alt...3600.0 s463 B
/v1/internal-556fdf0f/doi/10.1172/jci196819?callback=_alt...3600.0 s457 B
/v1/internal-556fdf0f/doi/10.1172/jci201762?callback=_alt...3600.0 s455 B
/v1/internal-556fdf0f/doi/10.1172/jci201075?callback=_alt...3600.0 s453 B
/v1/internal-556fdf0f/doi/10.1172/jci199850?callback=_alt...3600.0 s451 B
/v1/internal-556fdf0f/doi/10.1172/jci189044?callback=_alt...3600.0 s451 B
/v1/internal-556fdf0f/doi/10.1172/jci199725?callback=_alt...3600.0 s446 B
/v1/internal-556fdf0f/doi/10.1172/jci202577?callback=_alt...3600.0 s446 B
/v1/internal-556fdf0f/doi/10.1172/jci206748?callback=_alt...3600.0 s443 B
/v1/internal-556fdf0f/doi/10.1172/jci198815?callback=_alt...3600.0 s442 B
/v1/internal-556fdf0f/doi/10.1172/jci191340?callback=_alt...3600.0 s442 B
/v1/internal-556fdf0f/doi/10.1172/jci200062?callback=_alt...3600.0 s442 B
/v1/internal-556fdf0f/doi/10.1172/jci198730?callback=_alt...3600.0 s440 B
/v1/internal-556fdf0f/doi/10.1172/jci193812?callback=_alt...3600.0 s440 B
/v1/internal-556fdf0f/doi/10.1172/jci195336?callback=_alt...3600.0 s439 B
/v1/internal-556fdf0f/doi/10.1172/jci198708?callback=_alt...3600.0 s437 B
/v1/internal-556fdf0f/doi/10.1172/jci197923?callback=_alt...3600.0 s437 B
/v1/internal-556fdf0f/doi/10.1172/jci195411?callback=_alt...3600.0 s433 B
/v1/internal-556fdf0f/doi/10.1172/jci198076?callback=_alt...3600.0 s430 B
/v1/internal-556fdf0f/doi/10.1172/jci205442?callback=_alt...3600.0 s430 B
/v1/internal-556fdf0f/doi/10.1172/jci191735?callback=_alt...3600.0 s430 B
/v1/internal-556fdf0f/doi/10.1172/jci205029?callback=_alt...3600.0 s428 B
/v1/internal-556fdf0f/doi/10.1172/jci199035?callback=_alt...3600.0 s427 B
/v1/internal-556fdf0f/doi/10.1172/jci197271?callback=_alt...3600.0 s425 B
/v1/internal-556fdf0f/doi/10.1172/jci198835?callback=_alt...3600.0 s425 B
/v1/internal-556fdf0f/doi/10.1172/jci194721?callback=_alt...3600.0 s424 B
/v1/internal-556fdf0f/doi/10.1172/jci196788?callback=_alt...3600.0 s417 B
/v1/internal-556fdf0f/doi/10.1172/jci199838?callback=_alt...3600.0 s410 B
www.gstatic.com/recaptcha/api2/logo_48.png604800.0 s2.3 KiB

Your first network request is the most important. Reduce its latency by avoiding redirects, ensuring a fast server response, and enabling text compression.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Consider setting font-display to swap or optional to ensure text is consistently visible. swap can be further optimized to mitigate layout shifts with font metric overrides.

Why this matters

Performance issues directly impact user engagement and conversion rates.

URLEst Savings
/assets/fontawesome-webfont-fa79d127baca4558a0b973f5f514b...255 ms
dm5migu4zj3pb.cloudfront.net/fonts/klavika/woff/KlavikaWebBasicRegular.woff215 ms
dm5migu4zj3pb.cloudfront.net/fonts/klavika/woff/KlavikaWebBasicBold.woff145 ms
fonts.gstatic.com/s/roboto/v48/KFO7CnqEu92Fr1ME7kSn66aGLdTylUAMa3yUBHMdazQ.woff215 ms
fonts.gstatic.com/s/roboto/v48/KFO7CnqEu92Fr1ME7kSn66aGLdTylUAMa3yUBHMdazQ.woff25.0 ms

A forced reflow occurs when JavaScript queries geometric properties (such as offsetWidth) after styles have been invalidated by a change to the DOM state. This can result in poor performance. Learn more about forced reflows and possible mitigations.

Why this matters

Performance issues directly impact user engagement and conversion rates.

headings: [map[key:source label:Top function call valueType:source-location] map[granularity:1 key:reflowTime label:Total reflow time valueType:ms]]
items: [map[reflowTime:1.004 source:map[column:7686 line:1 type:source-location url:https://www.jci.org/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759fad32679209f5aef429b89f3aef.js urlProvider:network]]]
headings: [map[key:source label:Source valueType:source-location] map[granularity:1 key:reflowTime label:Total reflow time valueType:ms]]
items: [map[reflowTime:8.86 source:map[column:4013 line:0 type:source-location url:https://www.jci.org/assets/vendor/modernizr-2f68aa04c7424c280c5bc9db8b68f7f6ff70bcd38254c5b89383eac8e89b1781.js urlProvider:network]] map[reflowTime:0.544 source:map[column:5967 line:0 type:source-location url:https://www.jci.org/assets/vendor/modernizr-2f68aa04c7424c280c5bc9db8b68f7f6ff70bcd38254c5b89383eac8e89b1781.js urlProvider:network]] map[reflowTime:3.702 source:map[column:6497 line:0 type:source-location url:https://www.jci.org/assets/vendor/modernizr-2f68aa04c7424c280c5bc9db8b68f7f6ff70bcd38254c5b89383eac8e89b1781.js urlProvider:network]] map[reflowTime:0.43 source:map[column:1173 line:0 type:source-location url:https://www.jci.org/assets/vendor/modernizr-2f68aa04c7424c280c5bc9db8b68f7f6ff70bcd38254c5b89383eac8e89b1781.js urlProvider:network]] map[reflowTime:0.163 source:map[column:1198 line:0 type:source-location url:https://www.jci.org/assets/vendor/modernizr-2f68aa04c7424c280c5bc9db8b68f7f6ff70bcd38254c5b89383eac8e89b1781.js urlProvider:network]] map[reflowTime:207.941 source:map[type:text value:[unattributed]]] map[reflowTime:8.248 source:map[column:4873 line:2 type:source-location url:https://www.jci.org/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759fad32679209f5aef429b89f3aef.js urlProvider:network]] map[reflowTime:28.417 source:map[column:9549 line:2 type:source-location url:https://www.jci.org/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759fad32679209f5aef429b89f3aef.js urlProvider:network]] map[reflowTime:0.709 source:map[column:5896 line:2 type:source-location url:https://www.jci.org/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759fad32679209f5aef429b89f3aef.js urlProvider:network]] map[reflowTime:0.131 source:map[column:5988 line:2 type:source-location url:https://www.jci.org/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759fad32679209f5aef429b89f3aef.js urlProvider:network]] map[reflowTime:0.69 source:map[column:15254 line:1 type:source-location url:https://www.jci.org/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759fad32679209f5aef429b89f3aef.js urlProvider:network]] map[reflowTime:1.293 source:map[column:380 line:580 type:source-location url:https://www.gstatic.com/recaptcha/releases/gTpTIWhbKpxADzTzkcabhXN4/recaptcha__en.js urlProvider:network]] map[reflowTime:0.824 source:map[column:47 line:303 type:source-location url:https://www.gstatic.com/recaptcha/releases/gTpTIWhbKpxADzTzkcabhXN4/recaptcha__en.js urlProvider:network]] map[reflowTime:0.88 source:map[column:48581 line:18 type:source-location url:https://securepubads.g.doubleclick.net/pagead/managed/js/gpt/m202604160201/pubads_impl.js?cb=31097945 urlProvider:network]] map[reflowTime:0.184 source:map[column:237248 line:18 type:source-location url:https://securepubads.g.doubleclick.net/pagead/managed/js/gpt/m202604160201/pubads_impl.js?cb=31097945 urlProvider:network]] map[reflowTime:2.613 source:map[column:278 line:92 type:source-location url:https://www.google-analytics.com/analytics.js urlProvider:network]]]

Each subpart has specific improvement strategies. Ideally, most of the LCP time should be spent on loading the resources, not within delays.

Why this matters

Performance issues directly impact user engagement and conversion rates.

headings: [map[key:label label:Subpart valueType:text] map[key:duration label:Duration valueType:ms]]
items: [map[duration:8017.601 label:Time to first byte subpart:timeToFirstByte] map[duration:836.383 label:Element render delay subpart:elementRenderDelay]]
lhId: page-0-P
nodeLabel: Torres et al. report that disruption of endoplasmic reticulum–associated degrad…
path: 6,HTML,2,BODY,0,DIV,0,DIV,7,DIV,0,DIV,0,DIV,0,DIV,0,DIV,0,DIV,0,DIV,0,DIV,2,DIV,0,DIV,1,DIV,0,P
selector: div.row > div.small-12 > div > p
snippet: <p>

HTTP/2 and HTTP/3 offer many benefits over HTTP/1.1, such as multiplexing. Learn more about using modern HTTP.

Why this matters

Performance issues directly impact user engagement and conversion rates.

URLProtocol
www.jci.org/http/1.1
/assets/application-4e3473ed7442aa1dc35d11f58ed4edfbd690f...http/1.1
/assets/ie8/application-c9c1df9dc6f969fb6db3e6e1316b9ac16...http/1.1
/assets/ie8/ie8-head-e4cc6664a4e806f330a789c9756cfe50f1bb...http/1.1
/assets/vendor/modernizr-2f68aa04c7424c280c5bc9db8b68f7f6...http/1.1
/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759...http/1.1
/assets/ie8/application-8c033a599105d459c98ea08bf9ef15e25...http/1.1
/assets/ie8/ie8-1af1fadfa0df4a7f5fcf8fc444742398e0579e1d8...http/1.1
/assets/common/jci-spelled-out-white-on-transparent.20160...http/1.1
/assets/search-black-ba9b554d6f74b1c93d6e6ab71d1c9830c18a...http/1.1
/assets/common/jci-only-white-6c989e8f9744a714482158b8231...http/1.1
/assets/common/search-white-530f3f95b9080d73eba51eaeffdf1...http/1.1
dm5migu4zj3pb.cloudfront.net/volumes/136/8/136-8-cover.jpghttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199850/small/JCI199850.f1.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/205000/205029/small/JCI205029.f1.gifhttp/1.1
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dm5migu4zj3pb.cloudfront.net/manuscripts/205000/205442/small/JCI205442.f1.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/206000/206748/small/JCI206748.f1.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/201000/201075/small/JCI201075.f1.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/202000/202577/small/JCI202577.f1.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/189000/189044/small/JCI189044.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/191000/191735/small/JCI191735.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/193000/193812/small/JCI193812.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194139/small/JCI194139.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194207/small/JCI194207.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194721/small/JCI194721.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/195000/195411/small/JCI195411.f1.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/196000/196788/small/JCI196788.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/196000/196819/small/JCI196819.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197271/small/JCI197271.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197503/small/JCI197503.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197556/small/JCI197556.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197812/small/JCI197812.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197923/small/JCI197923.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198076/small/JCI198076.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198708/small/JCI198708.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198730/small/JCI198730.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198815/small/JCI198815.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198835/small/JCI198835.f1.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199035/small/JCI199035.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199725/small/JCI199725.f1.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/200000/200062/small/JCI200062.ga.gifhttp/1.1
dm5migu4zj3pb.cloudfront.net/manuscripts/201000/201762/small/JCI201762.ga.gifhttp/1.1
/assets/social/twitter-round-blue-78025a92064e3594e44e4cc...http/1.1
/assets/social/facebook-round-blue-2787910d46dcbdbee4bd34...http/1.1
/assets/social/rss-round-color-6f5fa8e93dc066ee4923a36ba6...http/1.1
dm5migu4zj3pb.cloudfront.net/fonts/klavika/woff/KlavikaWebBasicBold.woffhttp/1.1
/assets/fontawesome-webfont-fa79d127baca4558a0b973f5f514b...http/1.1
dm5migu4zj3pb.cloudfront.net/fonts/klavika/woff/KlavikaWebBasicRegular.woffhttp/1.1
www.jci.org/articles/subscriber_labelhttp/1.1
www.jci.org/404http/1.1

Avoid chaining critical requests by reducing the length of chains, reducing the download size of resources, or deferring the download of unnecessary resources to improve page load.

Why this matters

Performance issues directly impact user engagement and conversion rates.

description: [preconnect](https://developer.chrome.com/docs/lighthouse/performance/uses-rel-preconnect/) hints help the browser establish a connection earlier in the page load, saving time when the first request for that origin is made. The following are the origins that the page preconnected to.
title: Preconnected origins
description: Add [preconnect](https://developer.chrome.com/docs/lighthouse/performance/uses-rel-preconnect/) hints to your most important origins, but try to use no more than 4.
title: Preconnect candidates
value: No additional origins are good candidates for preconnecting

Reducing the download time of images can improve the perceived load time of the page and LCP. Learn more about optimizing image size

Why this matters

Performance issues directly impact user engagement and conversion rates.

URLResource SizeEst Savings
div.small-12 > div.row > div.large-3 > img.issue-cover div.small-12 > div.row > div.large-3 > img.issue-cover
dm5migu4zj3pb.cloudfront.net/volumes/136/8/136-8-cover.jpg33.0 KiB25.5 KiB
div#logo-bar > div.small-12 > a > img div#logo-bar > div.small-12 > a > img
/assets/common/jci-spelled-out-white-on-transparent.20160...15.9 KiB11.5 KiB

Requests are blocking the page's initial render, which may delay LCP. Deferring or inlining can move these network requests out of the critical path.

Why this matters

Performance issues directly impact user engagement and conversion rates.

URLTransfer SizeDuration
/recaptcha/enterprise.js?render=6LdqSIwsAAAAAMaqy5uLiYS-E...1.1 KiB370 ms

These insights are also available in the Chrome DevTools Performance Panel - record a trace to view more detailed information.

Redirects introduce additional delays before the page can be loaded. Learn how to avoid page redirects.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Estimated savings: 582 ms
URLTime Spent
jci.org/582 ms
www.jci.org/0.0 ms

Keep the server response time for the main document short because all other requests depend on it. Learn more about the Time to First Byte metric.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Estimated savings: 7.3 s
URLTime Spent
www.jci.org/7.4 s

Time to Interactive is the amount of time it takes for the page to become fully interactive. Learn more about the Time to Interactive metric.

Why this matters

Performance issues directly impact user engagement and conversion rates.

TTI

Diagnostics

Reduce unused rules from stylesheets and defer CSS not used for above-the-fold content to decrease bytes consumed by network activity. Learn how to reduce unused CSS.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Estimated savings: 0.0 ms 43.5 KiB
URLTransfer SizeEst Savings
/assets/application-4e3473ed7442aa1dc35d11f58ed4edfbd690f...46.9 KiB43.5 KiB

Consider reducing the time spent parsing, compiling and executing JS. You may find delivering smaller JS payloads helps with this. Learn how to minimize main-thread work

Why this matters

Performance issues directly impact user engagement and conversion rates.

CategoryTime Spent
Script Evaluation1.2 s
Other383 ms
Style & Layout277 ms
Script Parsing & Compilation171 ms
Rendering124 ms
Garbage Collection66 ms
Parse HTML & CSS42 ms

Reduce unused JavaScript and defer loading scripts until they are required to decrease bytes consumed by network activity. Learn how to reduce unused JavaScript.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Estimated savings: 0.0 ms 688.5 KiB
URLTransfer SizeEst Savings
/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759...347.6 KiB284.4 KiB
www.gstatic.com/recaptcha/releases/gTpTIWhbKpxADzTzkcabhXN4/recaptcha__en.js361.8 KiB156.2 KiB
/pagead/managed/js/gpt/m202604160201/pubads_impl.js?cb=31...187.7 KiB109.7 KiB
www.googletagmanager.com/gtag/js?id=G-2VCKF2JS2B&cx=c&_slc=1177.5 KiB72.2 KiB
www.googletagmanager.com/gtm.js?id=GTM-WTNK8H9141.8 KiB66.0 KiB

Large network payloads cost users real money and are highly correlated with long load times. Learn how to reduce payload sizes.

Why this matters

Performance issues directly impact user engagement and conversion rates.

URLTransfer Size
www.youtube.com/s/player/8456c9de/player_embed_es6.vflset/en_US/base.js436.5 KiB
www.gstatic.com/recaptcha/releases/gTpTIWhbKpxADzTzkcabhXN4/recaptcha__en.js362.4 KiB
www.gstatic.com/recaptcha/releases/gTpTIWhbKpxADzTzkcabhXN4/recaptcha__en.js361.9 KiB
/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759...347.9 KiB
/pagead/managed/js/gpt/m202604160201/pubads_impl.js?cb=31...187.7 KiB
/s/_/ytembeds/_/js/k=ytembeds.base.en_US.5f0apfZzpOA.2021...183.1 KiB
www.googletagmanager.com/gtag/js?id=G-2VCKF2JS2B&cx=c&_slc=1177.6 KiB
www.googletagmanager.com/gtm.js?id=GTM-WTNK8H9142.2 KiB
/s/_/ytembeds/_/js/k=ytembeds.base.en_US.5f0apfZzpOA.2021...140.1 KiB
/assets/fontawesome-webfont-fa79d127baca4558a0b973f5f514b...75.6 KiB

Set an explicit width and height on image elements to reduce layout shifts and improve CLS. Learn how to set image dimensions

Why this matters

Performance issues directly impact user engagement and conversion rates.

URL
div.small-12 > div.row > div.large-3 > img.issue-cover div.small-12 > div.row > div.large-3 > img.issue-cover
dm5migu4zj3pb.cloudfront.net/volumes/136/8/136-8-cover.jpg
div#logo-bar > div.small-12 > a > img div#logo-bar > div.small-12 > a > img
/assets/common/jci-spelled-out-white-on-transparent.20160...
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198730/small/JCI198730.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/202000/202577/small/JCI202577.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/201000/201075/small/JCI201075.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/195000/195411/small/JCI195411.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/206000/206748/small/JCI206748.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198835/small/JCI198835.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197271/small/JCI197271.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199035/small/JCI199035.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198815/small/JCI198815.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194139/small/JCI194139.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/191000/191735/small/JCI191735.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/196000/196819/small/JCI196819.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197812/small/JCI197812.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198708/small/JCI198708.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/198000/198076/small/JCI198076.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199725/small/JCI199725.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/196000/196788/small/JCI196788.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197556/small/JCI197556.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194721/small/JCI194721.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/199000/199850/small/JCI199850.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/205000/205029/small/JCI205029.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197923/small/JCI197923.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/194000/194207/small/JCI194207.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/205000/205273/small/JCI205273.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/189000/189044/small/JCI189044.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/201000/201762/small/JCI201762.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/205000/205442/small/JCI205442.f1.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/197000/197503/small/JCI197503.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/200000/200062/small/JCI200062.ga.gif
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
dm5migu4zj3pb.cloudfront.net/manuscripts/193000/193812/small/JCI193812.ga.gif
div.small-6 > div#social-links > a > img div.small-6 > div#social-links > a > img
/assets/social/twitter-round-blue-78025a92064e3594e44e4cc...
div.small-6 > div#social-links > a > img div.small-6 > div#social-links > a > img
/assets/social/facebook-round-blue-2787910d46dcbdbee4bd34...
div.small-6 > div#social-links > a > img div.small-6 > div#social-links > a > img
/assets/social/rss-round-color-6f5fa8e93dc066ee4923a36ba6...

More information about the performance of your application. These numbers don't directly affect the Performance score.

●Max Potential First Input Delay 120 ms
●Layout shift culprits
●Optimize DOM size
●Optimize viewport for mobile
●Minify CSS
●Minify JavaScript
●User Timing marks and measures 5 user timings
●JavaScript execution time 1.0 s
●Avoid long main-thread tasks 4 long tasks found
●Page didn't prevent back/forward cache restoration
●Network Requests
●Network Round Trip Times 130 ms
●Server Backend Latencies 60 ms
●Tasks
●Diagnostics
●Metrics
●Screenshot Thumbnails
●Final Screenshot
●Script Treemap Data
●Resources Summary
●Avoid large layout shifts 4 layout shifts found
○INP breakdown
○LCP request discovery
○Avoid non-composited animations
68

Accessibility

These checks highlight opportunities to improve the accessibility of your web app. Automatic detection can only detect a subset of issues and does not guarantee the accessibility of your web app, so manual testing is also encouraged.

Contrast

Low-contrast text is difficult or impossible for many users to read. Learn how to provide sufficient color contrast.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
In-Press Preview div.row > div.small-12 > a > span.label-in-press-preview
In-Press Preview div.row > div.small-12 > a > span.label-in-press-preview
In-Press Preview div.row > div.small-12 > a > span.label-in-press-preview
In-Press Preview div.row > div.small-12 > a > span.label-in-press-preview
In-Press Preview div.row > div.small-12 > a > span.label-in-press-preview
form > div.row > div.small-12 > input.button form > div.row > div.small-12 > input.button
form > div.row > div.small-12 > input.button form > div.row > div.small-12 > input.button

Low-contrast text is difficult or impossible for many users to read. Link text that is discernible improves the experience for users with low vision. Learn how to make links distinguishable.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
Torres et al. div.small-12 > div > p > a
Text div.small-12 > div.row > div.small-12 > a
PDF div.small-12 > div.row > div.small-12 > a
Text div.small-12 > div.row > div.small-12 > a
PDF div.small-12 > div.row > div.small-12 > a

These are opportunities to improve the legibility of your content.

Tables and lists

When definition lists are not properly marked up, screen readers may produce confusing or inaccurate output. Learn how to structure definition lists correctly.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
Review Series Immune signaling and function in neurodegeneration Yvonne L. Lat… div.small-12 > div.row > div.small-12 > dl.article-section
Commentaries Diet’s rapid effects on the thyroid gland challenge unidirectiona… div.small-12 > div.row > div.small-12 > dl.article-section
Research Letters Sinus mast cell accumulation and persistence suggest a unique… div.small-12 > div.row > div.small-12 > dl.article-section
Research Articles Inhibiting LSD1 unlocks retinoid AP-1 programming to activat… div.small-12 > div.row > div.small-12 > dl.article-section
Corrigendum Corrigendum to Type 2 diabetes candidate genes, including PAX5, ca… div.small-12 > div.row > div.small-12 > dl.article-section

These are opportunities to improve the experience of reading tabular or list data using assistive technology, like a screen reader.

Names and labels

Informative elements should aim for short, descriptive alternate text. Decorative elements can be ignored with an empty alt attribute. Learn more about the `alt` attribute.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
div#logo-bar > div.small-12 > a > img div#logo-bar > div.small-12 > a > img
div.small-12 > div.row > div.large-3 > img.issue-cover div.small-12 > div.row > div.large-3 > img.issue-cover
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img

When an image is being used as an `<input>` button, providing alternative text can help screen reader users understand the purpose of the button. Learn about input image alt text.

Why this matters

Informational: a Permissions-Policy directive showing feature -> allowed origins.

Source: MDN Permissions-Policy

Failing Elements
li.has-form > div#search-area > form > input li.has-form > div#search-area > form > input
form > div#search-div-offcanvas > div.small-4 > input#search-icon-offcanvas form > div#search-div-offcanvas > div.small-4 > input#search-icon-offcanvas

Screen reader users rely on frame titles to describe the contents of frames. Learn more about frame titles.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
div.row > div.small-12 > div.flex-video > iframe div.row > div.small-12 > div.flex-video > iframe

Link text (and alternate text for images, when used as links) that is discernible, unique, and focusable improves the navigation experience for screen reader users. Learn how to make links accessible.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
div.fixed > div#logo-bar > div.small-12 > a div.fixed > div#logo-bar > div.small-12 > a

These are opportunities to improve the semantics of the controls in your application. This may enhance the experience for users of assistive technology, like a screen reader.

Navigation

Properly ordered headings that do not skip levels convey the semantic structure of the page, making it easier to navigate and understand when using assistive technologies. Learn more about heading order.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
Go to section: div.small-12 > div.row > div.large-9 > h5

These are opportunities to improve keyboard navigation in your application.

Best practices

Touch targets with sufficient size and spacing help users who may have difficulty targeting small controls to activate the targets. Learn more about touch targets.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
Article has an altmetric score of 66 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 8 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 29 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 50 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 2 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 7 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 11 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 3 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 6 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 3 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 8 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 11 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 4 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 38 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 5 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 46 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 3 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 2 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 4 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 5 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 4 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 1 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 3 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 5 div.row > div.small-12 > span.altmetric-embed > a
Article has an altmetric score of 4 div.row > div.small-12 > span.altmetric-embed > a

One main landmark helps screen reader users navigate a web page. Learn more about landmarks.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
html.js html.js

These items highlight common accessibility best practices.

○Interactive controls are keyboard focusable
○Interactive elements indicate their purpose and state
○The page has a logical tab order
○Visual order on the page follows DOM order
○User focus is not accidentally trapped in a region
○The user's focus is directed to new content added to the page
○HTML5 landmark elements are used to improve navigation
○Offscreen content is hidden from assistive technology
○Custom controls have associated labels
○Custom controls have ARIA roles
●`[aria-*]` attributes match their roles
●`[aria-hidden="true"]` is not present on the document `<body>`
●`[role]`s have all required `[aria-*]` attributes
●`[role]` values are valid
●`[aria-*]` attributes have valid values
●`[aria-*]` attributes are valid and not misspelled
●Input buttons have discernible text.
●Form elements have associated labels
●`[user-scalable="no"]` is not used in the `<meta name="viewport">` element and the `[maximum-scale]` attribute is not less than 5.
●ARIA attributes are used as specified for the element's role
●Elements use only permitted ARIA attributes
●Definition list items are wrapped in `<dl>` elements
●Document has a `<title>` element
●`<html>` element has a `[lang]` attribute
●`<html>` element has a valid value for its `[lang]` attribute
●Lists contain only `<li>` elements and script supporting elements (`<script>` and `<template>`).
●List items (`<li>`) are contained within `<ul>`, `<ol>` or `<menu>` parent elements
●Deprecated ARIA roles were not used
●Identical links have the same purpose.
○`[accesskey]` values are unique
○`button`, `link`, and `menuitem` elements have accessible names
○Elements with `role="dialog"` or `role="alertdialog"` have accessible names.
○`[aria-hidden="true"]` elements do not contain focusable descendents
○ARIA input fields have accessible names
○ARIA `meter` elements have accessible names
○ARIA `progressbar` elements have accessible names
○Elements with an ARIA `[role]` that require children to contain a specific `[role]` have all required children.
○`[role]`s are contained by their required parent element
○Elements with the `role=text` attribute do not have focusable descendents.
○ARIA toggle fields have accessible names
○ARIA `tooltip` elements have accessible names
○ARIA `treeitem` elements have accessible names
○Buttons have an accessible name
○The page contains a heading, skip link, or landmark region
○ARIA IDs are unique
○No form fields have multiple labels
○`<html>` element has an `[xml:lang]` attribute with the same base language as the `[lang]` attribute.
○The document does not use `<meta http-equiv="refresh">`
○`<object>` elements have alternate text
○Select elements have associated label elements.
○Skip links are focusable.
○No element has a `[tabindex]` value greater than 0
○Cells in a `<table>` element that use the `[headers]` attribute refer to table cells within the same table.
○`<th>` elements and elements with `[role="columnheader"/"rowheader"]` have data cells they describe.
○`[lang]` attributes have a valid value
○`<video>` elements contain a `<track>` element with `[kind="captions"]`
○Tables have different content in the summary attribute and `<caption>`.
○All heading elements contain content.
○Uses ARIA roles only on compatible elements
○Image elements do not have `[alt]` attributes that are redundant text.
○Elements with visible text labels have matching accessible names.
○Tables use `<caption>` instead of cells with the `[colspan]` attribute to indicate a caption.
○`<td>` elements in a large `<table>` have one or more table headers.
92

Best Practices

User Experience

Image display dimensions should match natural aspect ratio. Learn more about image aspect ratio.

Why this matters

Performance issues directly impact user engagement and conversion rates.

URLAspect Ratio (Displayed)Aspect Ratio (Actual)
section.middle > h1.title > a > img section.middle > h1.title > a > img
/assets/common/jci-only-white-6c989e8f9744a714482158b8231...40 x 52 (0.77)66 x 52 (1.27)

General

Errors logged to the console indicate unresolved problems. They can come from network request failures and other browser concerns. Learn more about this errors in console diagnostic audit

Why this matters

Performance issues directly impact user engagement and conversion rates.

SourceDescription
s7.addthis.com/js/300/addthis_widget.js#pubid=ra-4d8389db4b0bb592
Failed to load resource: net::ERR_NAME_NOT_RESOLVED
s7.addthis.com/js/300/addthis_widget.js#pubid=ra-4d8389db4b0bb592
Failed to load resource: net::ERR_NAME_NOT_RESOLVED
www.jci.org/404
Failed to load resource: the server responded with a status of 404 (Not Found)

Source maps translate minified code to the original source code. This helps developers debug in production. In addition, Lighthouse is able to provide further insights. Consider deploying source maps to take advantage of these benefits. Learn more about source maps.

Why this matters

Performance issues directly impact user engagement and conversion rates.

URL
/assets/application-27f18b5fe3b7302e5b3e3c6d7cf9bb3f54759...
●Uses HTTPS
●Avoids deprecated APIs
●Avoids third-party cookies
●Allows users to paste into input fields
●Avoids requesting the geolocation permission on page load
●Avoids requesting the notification permission on page load
●Serves images with appropriate resolution
●Page has the HTML doctype
●Properly defines charset
●No issues in the `Issues` panel in Chrome Devtools
●Ensure CSP is effective against XSS attacks
●Use a strong HSTS policy
●Ensure proper origin isolation with COOP
●Mitigate DOM-based XSS with Trusted Types
●Detected JavaScript libraries
○Redirects HTTP traffic to HTTPS
○Mitigate clickjacking with XFO or CSP
67

SEO

These checks ensure that your page is following basic search engine optimization advice. There are many additional factors Lighthouse does not score here that may affect your search ranking, including performance on Core Web Vitals. Learn more about Google Search Essentials.

Content Best Practices

Meta descriptions may be included in search results to concisely summarize page content. Learn more about the meta description.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Descriptive link text helps search engines understand your content. Learn how to make links more accessible.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Link destinationLink Text
www.jci.org/in-press-previewMore
www.jci.org/review_seriesMore
www.jci.org/tags/reviewsMore
www.jci.org/videos/video_abstractsMore

Informative elements should aim for short, descriptive alternate text. Decorative elements can be ignored with an empty alt attribute. Learn more about the `alt` attribute.

Why this matters

Performance issues directly impact user engagement and conversion rates.

Failing Elements
div#logo-bar > div.small-12 > a > img div#logo-bar > div.small-12 > a > img
div.small-12 > div.row > div.large-3 > img.issue-cover div.small-12 > div.row > div.large-3 > img.issue-cover
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img
div.row > div.medium-3 > a > img div.row > div.medium-3 > a > img

Format your HTML in a way that enables crawlers to better understand your app’s content.

Crawling and Indexing

Search engines may use `href` attributes on links to crawl websites. Ensure that the `href` attribute of anchor elements links to an appropriate destination, so more pages of the site can be discovered. Learn how to make links crawlable

Why this matters

Performance issues directly impact user engagement and conversion rates.

Uncrawlable Link
Back ul.dropdown > li.title > h5 > a
Back ul.dropdown > li.title > h5 > a
Back ul.dropdown > li.title > h5 > a
Back ul.dropdown > li.title > h5 > a
div.inner-wrap > nav#small-navbar > section.left-small > a.left-off-canvas-toggle

To appear in search results, crawlers need access to your app.

○Structured data is valid
●Page isn’t blocked from indexing
●Document has a `<title>` element
●Page has successful HTTP status code
●robots.txt is valid
●Document has a valid `hreflang`
○Document has a valid `rel=canonical`

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